<cc1:AnimationExtender ID="ae" runat="server" TargetControlID="Button1">
     <Animations>
          <OnClick>
               <Sequence>
                    <EnableAction Enabled="false" />
                    <Parallel>
                         <FadeOut Duration="1.5" Fps="24" AnimationTarget="Panel1" />
                         <Resize Width="1000" Height="150" Unit="px"
                              AnimationTarget="Panel1" />
                    </Parallel>
               </Sequence>
          </OnClick>
     </Animations>

    </cc1:AnimationExtender>

<hr />

<asp:Panel ID="Panel1" runat="server" CssClass="panelClass">
     ASP.NET AJAX is a free framework for quickly creating a new generation of more
     efficient, more interactive and highly-personalized Web experiences that work
     across all the most popular browsers.<br />
     ASP.NET AJAX is a free framework for quickly creating a new generation of more
     efficient, more interactive and highly-personalized Web experiences that work
     across all the most popular browsers.<br />
     ASP.NET AJAX is a free framework for quickly creating a new generation of more
     efficient, more interactive and highly-personalized Web experiences that work
     across all the most popular browsers.<br />
</asp:Panel>

    <input id="Button1"  runat="server" type="button" value="button" />
    <cc1:AnimationExtender id="MyExtender"
  runat="server" TargetControlID="Button1">
  <Animations>
    <OnClick>
      <Sequence>
  <EnableAction Enabled="false" />
  <Color AnimationTarget="Panel1"
    Duration="1"
    StartValue="#FF0000"
    EndValue="#666666"
    Property="style"
    PropertyKey="backgroundColor" />
  <Color AnimationTarget="Panel1"
    Duration="1"
    StartValue="#FF0000"
    EndValue="#666666"
    Property="style"
    PropertyKey="backgroundColor" />
  <EnableAction Enabled="true" />
</Sequence>
    </OnClick>
  </Animations>
  </cc1:AnimationExtender>